<Suppliers Price>

valencene

Names

[ CAS No. ]:
4630-07-3

[ Name ]:
valencene

[Synonym ]:
FEMA 3443
(3R,4aS,5R)-4a,5-Dimethyl-3-isopropenyl-1,2,3,4,4a,5,6,7-octahydronaphthalene
(1R,7R,8aS)-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)naphthalene
MFCD00075884
(R)-Valencene
Valencen
EINECS 225-047-6
VALENCE
VALENCENE 85
VALENCENE

Biological Activity

[Description]:

Valencene is a sesquiterpene isolated from Cyperus rotundus, possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene is used to flavor foods and drinks[1][2][3].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Yang IJ, et al. Inhibitory Effect of Valencene on the Development of Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice. Evid Based Complement Alternat Med. 2016;2016:9370893.

[2]. Frohwitter J, et al. Production of the sesquiterpene (+)-valencene by metabolically engineered Corynebacterium glutamicum. J Biotechnol. 2014 Dec 10;191:205-13.

[3]. Marques FM, et al. In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway. Inflammopharmacology. 2019 Apr;27(2):281-289.

Chemical & Physical Properties

[ Density]:
0.89g/cm3

[ Boiling Point ]:
270.5ºC at 760mmHg

[ Molecular Formula ]:
C15H24

[ Molecular Weight ]:
204.35100

[ Flash Point ]:
106ºC

[ Exact Mass ]:
204.18800

[ LogP ]:
4.72520

[ Index of Refraction ]:
n20/D 1.504(lit.)

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds