Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI)

Modify Date: 2023-01-14 21:29:43

Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI) Structure
Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI) structure
Common Name Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI)
CAS Number 4627-40-1 Molecular Weight 335.24
Density 2.11g/cm3 Boiling Point 462.3ºC at 760mmHg
Molecular Formula C11H12F3N5O4 Melting Point N/A
MSDS N/A Flash Point 233.4ºC

 Use of Adenosine,2-(trifluoromethyl)- (7CI,8CI,9CI)


2-Trifluoromethyl adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name (2R,3R,4S,5R)-2-[6-amino-2-(trifluoromethyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

  Biological Activity

Description 2-Trifluoromethyl adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.11g/cm3
Boiling Point 462.3ºC at 760mmHg
Molecular Formula C11H12F3N5O4
Molecular Weight 335.24
Flash Point 233.4ºC
Exact Mass 335.08400
PSA 139.54000
Index of Refraction 1.753

 Synonyms

Adenosine,2-(trifluoromethyl)-(7CI,8CI,9CI)
2-Trifluoromethyladenosine
2-Trifluormethyl-adenosin