a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-

Modify Date: 2024-01-10 22:07:42

a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)- Structure
a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)- structure
Common Name a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-
CAS Number 4613-62-1 Molecular Weight 244.28
Density 1.123g/cm3 Boiling Point 291ºC at 760mmHg
Molecular Formula C12H20O5 Melting Point N/A
MSDS N/A Flash Point 112ºC

 Use of a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-


3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-(2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole

  Biological Activity

Description 3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.123g/cm3
Boiling Point 291ºC at 760mmHg
Molecular Formula C12H20O5
Molecular Weight 244.28
Flash Point 112ºC
Exact Mass 244.13100
PSA 46.15000
LogP 1.40440
Index of Refraction 1.461
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