2-Bromo-4-fluoro-1-methoxybenzene

Modify Date: 2025-08-21 11:50:36

2-Bromo-4-fluoro-1-methoxybenzene structure	Common Name	2-Bromo-4-fluoro-1-methoxybenzene
	CAS Number	452-08-4	Molecular Weight	205.02
	Density	1.5±0.1 g/cm3	Boiling Point	273.6±0.0 °C at 760 mmHg
	Molecular Formula	C₇H₆BrFO	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	98.3±0.0 °C
	Symbol	GHS07	Signal Word	Warning

Use of 2-Bromo-4-fluoro-1-methoxybenzene

2-Bromo-4-fluoroanisole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	2-Bromo-4-fluoroanisole
Synonym	More Synonyms

Description	2-Bromo-4-fluoroanisole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others

Density	1.5±0.1 g/cm3
Boiling Point	273.6±0.0 °C at 760 mmHg
Molecular Formula	C₇H₆BrFO
Molecular Weight	205.02
Flash Point	98.3±0.0 °C
Exact Mass	203.958603
PSA	9.23000
LogP	2.82
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.519

2-Bromo-4-fluoro-1-methoxybenzene MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2909309090

2-Bromo-4-fluor...

CAS#:496-69-5

methyl iodide

CAS#:74-88-4

~94%

2-Bromo-4-fluor...

CAS#:452-08-4

Literature: Gu, Shuang-Xi; Zhang, Xuan; He, Qiu-Qin; Yang, Liu-Meng; Ma, Xiao-Dong; Zheng, Yong-Tang; Yang, Shi-Qiong; Chen, Fen-Er Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 14 p. 4220 - 4226

4-Fluorobenzyl ...

CAS#:459-60-9

~99%

2-Bromo-4-fluor...

CAS#:452-08-4

Literature: Castellonese, Paul; Villa, Pierre Helvetica Chimica Acta, 1983 , vol. 66, # 4 p. 1068 - 1077

5-Fluoro-o-anisidine

CAS#:1978-39-8

2-Bromo-4-fluor...

CAS#:452-08-4

Literature: Finger et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97

4-Fluoro-1-meth...

CAS#:445-83-0

2-Bromo-4-fluor...

CAS#:452-08-4

Literature: Finger et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 94,95, 97

Precursor 5
CAS#:496-69-5 2-Bromo-4-fluor... CAS#:74-88-4 methyl iodide CAS#:459-60-9 4-Fluorobenzyl ... CAS#:1978-39-8 5-Fluoro-o-anisidine
CAS#:445-83-0 4-Fluoro-1-meth...
DownStream 8
CAS#:496-69-5 2-Bromo-4-fluor... CAS#:426831-32-5 5-Fluoro-2-meth... CAS#:1441770-44-0 4-(5-fluoro-2-m... CAS#:179897-92-8 1-Bromo-5-fluor...
CAS#:189628-38-4 5-Fluoro-2-meth... CAS#:188132-02-7 5-fluoro-2-meth... CAS#:72955-97-6 5-Fluoro-2-meth... CAS#:19415-51-1 5-Fluoro-2-meth...

HS Code	2909309090
Summary	2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Telescoped approach to aryl hydroxymethylation in the synthesis of a key pharmaceutical intermediate.

J. Org. Chem. 78(12) , 5955-63, (2013)

An efficient synthetic approach leading to introduction of the hydroxymethyl group to an aryl moiety via combination of the Bouveault formylation and hydride reduction has been optimized using a ratio...

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2-Bromo-4-fluoro-1-methoxybenzene

MFCD00012014