PCNA I1

Modify Date: 2025-08-25 18:26:14

PCNA I1 Structure
PCNA I1 structure
 Common Name PCNA I1
CAS Number 444930-42-1 Molecular Weight 310.370
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C17H14N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PCNA I1


PCNA-I1 is a potent PCNA (proliferating cell nuclear antigen) inhibitor. PCNA-I1 directly binds PCNA trimers with a Kd of 0.41 μM and exhibits antitumor activity both in vitro and in vivo[1].

 Names

Name N'-[(E)-(1-Hydroxy-2-naphthyl)methylene]-3-methyl-2-thiophenecarbohydrazide
Synonym More Synonyms

 PCNA I1 Biological Activity

Description PCNA-I1 is a potent PCNA (proliferating cell nuclear antigen) inhibitor. PCNA-I1 directly binds PCNA trimers with a Kd of 0.41 μM and exhibits antitumor activity both in vitro and in vivo[1].
Related Catalog
References

[1]. Tan Z, et al. Small-molecule targeting of proliferating cell nuclear antigen chromatin association inhibits tumor cell growth. Mol Pharmacol. 2012 Jun;81(6):811-9.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C17H14N2O2S
Molecular Weight 310.370
Exact Mass 310.077606
LogP 5.30
Index of Refraction 1.667

 Synonyms

2-Thiophenecarboxylic acid, 3-methyl-, 2-[(1E)-(1-hydroxy-2-naphthalenyl)methylene]hydrazide
MFCD02606552
N'-[(E)-(1-Hydroxy-2-naphthyl)methylene]-3-methyl-2-thiophenecarbohydrazide
N'-[(E)-(1-Hydroxy-2-naphthyl)methylene]-3-methylthiophene-2-carbohydrazide
PCNA-I 1
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Chemsrc provides PCNA I1(CAS#:444930-42-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PCNA I1 are included as well.>> amp version: PCNA I1

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