Lepadin E
Modify Date: 2024-09-15 12:08:03
Lepadin E structure
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Common Name | Lepadin E | ||
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| CAS Number | 444914-19-6 | Molecular Weight | 421.66 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H47NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lepadin ELepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect[1]. |
| Name | Lepadin E |
|---|
| Description | Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect[1]. |
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| Related Catalog | |
| In Vivo | Lepadin E |
| References |
| Molecular Formula | C26H47NO3 |
|---|---|
| Molecular Weight | 421.66 |