Cc-3060
Modify Date: 2025-08-25 15:15:31
Cc-3060 structure
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Common Name | Cc-3060 | ||
|---|---|---|---|---|
| CAS Number | 444288-86-2 | Molecular Weight | 403.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H17N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cc-3060CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1]. |
| Name | CC-3060 |
|---|
| Description | CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1]. |
|---|---|
| Related Catalog | |
| Target |
DC50: 0.47 nM (ZBTB16 in HT-1080 cells)[1] |
| References |
| Molecular Formula | C22H17N3O5 |
|---|---|
| Molecular Weight | 403.39 |
| InChIKey | GRICLJZNEMDVMA-UHFFFAOYSA-N |
| SMILES | O=C1CCC(N2C(=O)c3cccc(NCc4cc5ccccc5o4)c3C2=O)C(=O)N1 |