Top Suppliers:I want be here

444288-86-2

444288-86-2 structure
444288-86-2 structure
  • Name: Cc-3060
  • Chemical Name: CC-3060
  • CAS Number: 444288-86-2
  • Molecular Formula: C22H17N3O5
  • Molecular Weight: 403.39
  • Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
  • Create Date: 2024-09-16 14:05:09
  • Modify Date: 2025-08-25 15:15:31
  • CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1].

Name CC-3060
Description CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1].
Related Catalog
Target

DC50: 0.47 nM (ZBTB16 in HT-1080 cells)[1]

References

[1]. Matyskiela ME, et al. Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons. ACS Chem Biol. 2020 Dec 18;15(12):3149-3158.

Molecular Formula C22H17N3O5
Molecular Weight 403.39
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.