LNK754
Modify Date: 2025-08-25 09:35:26
LNK754 structure
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Common Name | LNK754 | ||
|---|---|---|---|---|
| CAS Number | 439153-64-7 | Molecular Weight | 479.96 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H22ClN3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LNK754LNK754 is a farnesyltransferase inhibitor, used for the treatment of cancer and Alzheimer's disease. |
| Name | LNK754 |
|---|---|
| Synonym | More Synonyms |
| Description | LNK754 is a farnesyltransferase inhibitor, used for the treatment of cancer and Alzheimer's disease. |
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| Related Catalog | |
| In Vivo | LNK-754 (0.9 mg/kg) significantly reduces α-synuclein plaques in a mouse model of PD, APP(SL), at 6 months of age for 3 months[1]. |
| References |
[1]. Keith T Gagnon. HD Therapeutics-CHDI Fifth Annual Conference. IDrugs. 2010 Apr;13(4):219-23. |
| Molecular Formula | C29H22ClN3O2 |
|---|---|
| Molecular Weight | 479.96 |
| Storage condition | 2-8℃ |
| (2R,3R)-2,3-Dihydroxysuccinic acid - 6-[(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-ethynylphenyl)-1-methyl-2(1H)-quinolinone (1:1) |
| Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with 6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-ethynylphenyl)-1-methyl-2(1H)-quinolinone (1:1) |