Monomethyl phthalate

Modify Date: 2024-01-03 09:59:58

Monomethyl phthalate Structure
Monomethyl phthalate structure
Common Name Monomethyl phthalate
CAS Number 4376-18-5 Molecular Weight 180.157
Density 1.3±0.1 g/cm3 Boiling Point 328.9±25.0 °C at 760 mmHg
Molecular Formula C9H8O4 Melting Point 82-84 °C(lit.)
MSDS Chinese USA Flash Point 134.7±16.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Monomethyl phthalate


Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule[1].

 Names

Name methyl hydrogen phthalate
Synonym More Synonyms

 Monomethyl phthalate Biological Activity

Description Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule[1].
Related Catalog
References

[1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 328.9±25.0 °C at 760 mmHg
Melting Point 82-84 °C(lit.)
Molecular Formula C9H8O4
Molecular Weight 180.157
Flash Point 134.7±16.7 °C
Exact Mass 180.042252
PSA 63.60000
LogP 1.13
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.556
Storage condition Refrigerator

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles6

More Articles
Feasibility of ultra-high performance liquid and gas chromatography coupled to mass spectrometry for accurate determination of primary and secondary phthalate metabolites in urine samples.

Anal. Chim. Acta 853 , 625-36, (2014)

Phthalates (PAEs) are ubiquitous toxic chemical compounds. During the last few years, some phthalate metabolites (MPAEs) have been proposed as appropriate biomarkers in human urine samples to determin...

Monitoring of PAEMs and beta-agonists in urine for a small group of experimental subjects and PAEs and beta-agonists in drinking water consumed by the same subjects.

J. Hazard. Mater. 277 , 169-79, (2014)

This 5-month study contains two parts: (1) to monitor the concentrations of 11 phthalate esters metabolites (PAEMs) and two beta-agonists in human urine samples collected from a small group of consent...

Phthalate Metabolites in Urine Samples from School Children in Taipei, Taiwan.

Arch. Environ. Contam. Toxicol. 69 , 202-7, (2015)

In 2011, Taiwan authorities reported that two phthalates, including di-(2-ethylhexyl) phthalate and di-iso-nonyl phthalate, were intentionally introduced into a variety of foods and beverages during t...

 Synonyms

1,2-Benzenedicarboxylic acid, monomethyl ester
Phthalic acid methyl ester
2-methoxycarbonylbenzoic acid
2-(Methoxycarbonyl)benzoic acid
Monomethyl phthalate
METHYL HYDROGEN PHTHALATE
phthalic acid, mono-methyl ester
MFCD00002466
1,2-Benzenedicarboxylic acid monomethyl ester
EINECS 224-476-6
Phthalic acid monomethyl ester
mono-Methyl phthalate
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