Curine

Modify Date: 2025-08-20 16:31:14

Curine structure	Common Name	Curine
	CAS Number	436-05-5	Molecular Weight	594.697
	Density	1.2±0.1 g/cm3	Boiling Point	706.5±60.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₃₈N₂O₆	Melting Point	213°; mp 221° in vacuo; mp 161°
	MSDS	N/A	Flash Point	381.1±32.9 °C

Use of Curine

(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production[1].

Name	curine
Synonym	More Synonyms

Description	(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production[1].
Related Catalog	Research Areas >> Endocrinology
Target	EP2
References	[1]. Leite FC, et al. Curine, an alkaloid isolated from Chondrodendron platyphyllum inhibits prostaglandin E2 in experimental models of inflammation and pain. Planta Med. 2014 Aug;80(13):1072-8.

Density	1.2±0.1 g/cm3
Boiling Point	706.5±60.0 °C at 760 mmHg
Melting Point	213°; mp 221° in vacuo; mp 161°
Molecular Formula	C₃₆H₃₈N₂O₆
Molecular Weight	594.697
Flash Point	381.1±32.9 °C
Exact Mass	594.273010
PSA	83.86000
LogP	4.12
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.620
InChIKey	NGZXDRGWBULKFA-VSGBNLITSA-N
SMILES	COc1cc2c3cc1Oc1cc(ccc1O)CC1c4c(cc(OC)c(O)c4Oc4ccc(cc4)CC3N(C)CC2)CCN1C
Storage condition	2-8℃