Curine

Names

[ CAS No. ]:
436-05-5

[ Name ]:
Curine

[Synonym ]:
Chondodendrine
1-Curine
l-Curine
Einecs 207-109-4
(1β)-6,6'-Dimethoxy-2,2'-dimethyltubocuraran-7',12'-diol
(-)-BEBEERINE
1-Bebeerine
Chonodoendrine (L)
L-BEBEERINE
d-bebeerine
(+-)-chondrodendrine

Biological Activity

[Description]:

(-)-Curine is an orally active bisbenzylisoquinoline alkaloid isolated from Chondrodendron platyphyllum. (-)-Curine presents anti-inflammatory and analgesic effects at nontoxic doses, at least in part, resulting from the inhibition of prostaglandin E2 production[1].

[Related Catalog]:

Research Areas >> Endocrinology

[Target]

EP2

[References]

[1]. Leite FC, et al. Curine, an alkaloid isolated from Chondrodendron platyphyllum inhibits prostaglandin E2 in experimental models of inflammation and pain. Planta Med. 2014 Aug;80(13):1072-8.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
706.5±60.0 °C at 760 mmHg

[ Melting Point ]:
213°; mp 221° in vacuo; mp 161°

[ Molecular Formula ]:
C₃₆H₃₈N₂O₆

[ Molecular Weight ]:
594.697

[ Flash Point ]:
381.1±32.9 °C

[ Exact Mass ]:
594.273010

[ PSA ]:
83.86000

[ LogP ]:
4.12

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
T+: Very toxic;

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
22-36/37/39-45

[ RIDADR ]:
UN 1544

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.