Z-590
Modify Date: 2025-09-03 12:47:51
Z-590 structure
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Common Name | Z-590 | ||
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| CAS Number | 433954-52-0 | Molecular Weight | 376.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H16N2O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Z-590Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity; significantly decreases the production of nitric oxide (NO), TNF-α, interleukin (IL)-6, IL-1β, cyclooxygenase (COX-2), inducible nitric oxide synthase (iNOS) as well as reactive oxygen species (ROS) involved in inhibiting MAKPs signalling pathway in LPS-stimulated microglia cells; suppresses cartilage destruction in adjuvant-induced arthritis via inhibition of macrophage inflammatory activatio in vivo. |
| Name | Z-590 |
|---|
| Description | Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity; significantly decreases the production of nitric oxide (NO), TNF-α, interleukin (IL)-6, IL-1β, cyclooxygenase (COX-2), inducible nitric oxide synthase (iNOS) as well as reactive oxygen species (ROS) involved in inhibiting MAKPs signalling pathway in LPS-stimulated microglia cells; suppresses cartilage destruction in adjuvant-induced arthritis via inhibition of macrophage inflammatory activatio in vivo. |
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| References | References 1. Zhang Z, et al. Immunopharmacol Immunotoxicol. 2018 Apr;40(2):149-157. 2. Zhang Y, et al. Clin Exp Pharmacol Physiol. 2016 Nov;43(11):1134-1144. View Related Products by Target Other Targets |
| Molecular Formula | C21H16N2O3S |
|---|---|
| Molecular Weight | 376.43 |