Triadimefon

Modify Date: 2025-08-21 16:40:46

Triadimefon structure	Common Name	Triadimefon
	CAS Number	43121-43-3	Molecular Weight	293.749
	Density	1.2±0.1 g/cm3	Boiling Point	441.9±55.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₁₆ClN₃O₂	Melting Point	82°C
	MSDS	Chinese USA	Flash Point	221.0±31.5 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of Triadimefon

Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.

Name	triadimefon
Synonym	More Synonyms

Description	Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.
Related Catalog	Signaling Pathways >> Anti-infection >> Fungal

Density	1.2±0.1 g/cm3
Boiling Point	441.9±55.0 °C at 760 mmHg
Melting Point	82°C
Molecular Formula	C₁₄H₁₆ClN₃O₂
Molecular Weight	293.749
Flash Point	221.0±31.5 °C
Exact Mass	293.093109
PSA	57.01000
LogP	2.77
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.580
Water Solubility	0.026 G/100 ML

Triadimefon MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EL7100000

CHEMICAL NAME :: 2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-y l)-

CAS REGISTRY NUMBER :: 43121-43-3

BEILSTEIN REFERENCE NO. :: 0619231

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C14-H16-Cl-N3-O2

MOLECULAR WEIGHT :: 293.78

WISWESSER LINE NOTATION :: T5NN DNJ AYOR DG&VX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 363 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2450 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2337 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5800 ug/m3/17W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Blood - methemoglobinemia-carboxyhemoglobin Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5800 ug/m3/17W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Blood - methemoglobinemia-carboxyhemoglobin Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,157,1995 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H317-H410
Precautionary Statements	P280-P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn,N,T,F
Risk Phrases	R22
Safety Phrases	24-37-61-45-36/37
RIDADR	2588
WGK Germany	3
RTECS	EL7100000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933990014

3-trifluorometh...

CAS#:99705-50-7

(E)-Methyl-2-(2...

CAS#:133409-72-0

~66%

Triadimefon

CAS#:43121-43-3

Literature: RALLIS INDIA LTD.; KAMARAJ, Pasumpon; SATAM, Vijay, Shrikant; AJJANNA, Mahalingappa, Sridhara; NANDI, Tapaskumar; BOBADE, Anna; SHINDE, Ravindra; NAIK, Parag; MOHITE, Dhanaji; KADAM, Subhash; HINDUPUR, Rama, Mohan; PATI, Hari, Narayan; MANE, Avinash; VADIRAJ, Suphala, Gopinath; VENKATESH, Prabhu, Moodbidri Patent: WO2013/144924 A1, 2013 ; Location in patent: Page/Page column 33; 34 ;

(E)-METHYL 2-(M...

CAS#:120974-97-2

Triadimefon

CAS#:43121-43-3

Precursor 3
CAS#:99705-50-7 3-trifluorometh... CAS#:133409-72-0 (E)-Methyl-2-(2... CAS#:120974-97-2 (E)-METHYL 2-(M...
DownStream 5
CAS#:55219-65-3 TRIADIMENOL CAS#:82200-72-4 Triadimenol B CAS#:89482-17-7 TRIADIMENOL CAS#:43121-37-5 1-([1,1'-biphen...
CAS#:43121-41-1 1-phenoxy-3,3-d...

HS Code	2933990014
Summary	2933990014 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1h-1,2,4-triazol-1-yl)butan-2-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Is the amphibian X. laevis WEC a good alternative method to rodent WEC teratogenicity assay? The example of the three triazole derivative fungicides Triadimefon, Tebuconazole, Cyproconazole.

Reprod. Toxicol. 32(2) , 220-6, (2011)

The aim of the present work is the assessment of teratogenic effects of three triazole-derived fungicides (Triadimefon, FON, Tebuconazole, TEBU, Cyproconazole, CYPRO) on rat and Xenopus laevis embryos...

Stage-dependent abnormalities induced by the fungicide triadimefon in the mouse.

Reprod. Toxicol. 31(2) , 194-9, (2011)

Aim of this work is the study of abnormalities induced by the triazole triadimefon (FON) administered to pregnant mice at E8, E9, E10, E11 or E12. Pregnant CD-1 mouse were gavaged with FON 500 mg/kg a...

Changes of thyroid hormone levels and related gene expression in zebrafish on early life stage exposure to triadimefon.

Environ. Toxicol. Pharmacol. 32(3) , 472-7, (2011)

In this study, zebrafish was exposed to triadimefon. Thyroid hormones levels and the expression of related genes in the hypothalamic-pituitary-thyroid (HPT) axis, including thyroid-stimulating hormone...

2-Butanone, 1- (4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-

Triadimefone

UNII:1HW039CJF0

Triadimeform

MILTEK

MFCD00055506

1-(4-Chlorphenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-on

2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-

ACIZOL

BAY 6681F

1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one

1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one

BAY 6681 F

BAY-MEB-6447

Bay MEB 6447

Fenxiunin

SAMETON

ROFON

Azocene

1-(4-Chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone

OTRIA

EINECS 256-103-8

(RS)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one

NUREX

DAYTON

Triadimefon

Amiral

TYPHON

rac-(1R)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Triadimefon
Price: Check
Purity: 99.8%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Triadimefon
Price: ￥178.0/1ml ￥178.0/1ml
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Triadimefon
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Triadimefon
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Triadimefon
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Triadimefon
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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Triadimefon

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Triadimefon Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

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