7-Hydroxymethyl-10,11-MDCPT

7-Hydroxymethyl-10,11-MDCPT Structure
7-Hydroxymethyl-10,11-MDCPT structure
Common Name 7-Hydroxymethyl-10,11-MDCPT
CAS Number 428816-69-7 Molecular Weight 422.39
Density N/A Boiling Point N/A
Molecular Formula C22H18N2O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 7-Hydroxymethyl-10,11-MDCPT


7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].

 Names

Name 7-Hydroxymethyl-10,11-MDCPT

 7-Hydroxymethyl-10,11-MDCPT Biological Activity

Description 7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].
Related Catalog
References

[1]. Wadkins RM, et al. Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I. Cancer Res. 2004 Sep 15;64(18):6679-83.  

 Chemical & Physical Properties

Molecular Formula C22H18N2O7
Molecular Weight 422.39
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