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428816-69-7

428816-69-7 structure

428816-69-7 structure

Name: 7-Hydroxymethyl-10,11-MDCPT
Chemical Name: 7-Hydroxymethyl-10,11-MDCPT
CAS Number: 428816-69-7
Molecular Formula: C₂₂H₁₈N₂O₇
Molecular Weight: 422.39
Catalog: Research Areas Others
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7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].

Name	7-Hydroxymethyl-10,11-MDCPT

Description	7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wadkins RM, et al. Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I. Cancer Res. 2004 Sep 15;64(18):6679-83.

Molecular Formula	C₂₂H₁₈N₂O₇
Molecular Weight	422.39

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