TAK-700 (Orteronel)
Modify Date: 2024-01-03 11:49:41
TAK-700 (Orteronel) structure
|
Common Name | TAK-700 (Orteronel) | ||
|---|---|---|---|---|
| CAS Number | 426219-18-3 | Molecular Weight | 307.346 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 685.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H17N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 368.2±28.7 °C | |
Use of TAK-700 (Orteronel)Orteronel (racemic) is a mixture of S-Orteronel and R-Orteronel isomers. Orteronel, aslo known as TAK-700, is an orally bioavailable non-steroidal androgen synthesis inhibitor of steroid 17alpha-monooxygenase (17,20 lyase) with potential antiandrogen activity. TAK-700 binds to and inhibits the steroid 17alpha-monooxygenase in both the testes and adrenal glands, thereby inhibiting androgen production. This may decrease androgen-dependent growth signaling and may inhibit cell proliferation of androgen-dependent tumor cells. |
| Name | 6-(7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 685.1±45.0 °C at 760 mmHg |
| Molecular Formula | C18H17N3O2 |
| Molecular Weight | 307.346 |
| Flash Point | 368.2±28.7 °C |
| Exact Mass | 307.132080 |
| PSA | 67.15000 |
| LogP | -0.13 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.695 |
| Storage condition | -20℃ |
| Precursor 9 | |
|---|---|
| DownStream 2 | |
![6-[1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide Structure](https://image.chemsrc.com/caspic/176/566200-77-9.png)
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CAS#:426219-35-4![5H-PYRROLO[1,2-C]IMIDAZOL-7(6H)-ONE Structure](https://image.chemsrc.com/caspic/077/426219-43-4.png)
CAS#:426219-43-4
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CAS#:426219-46-7![N,N-diisopropyl-6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)methyl]-2-naphthamide Structure](https://image.chemsrc.com/caspic/099/1346155-54-1.png)
CAS#:1346155-54-1![N,N-diisopropyl-6-[(1-trityl-1H-imidazol-4-yl)carbonyl]-2-naphthamide Structure](https://image.chemsrc.com/caspic/425/426219-47-8.png)
CAS#:426219-47-8
CAS#:566939-85-3![6-[(7R)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide structure](https://image.chemsrc.com/caspic/152/752243-39-3.png)
CAS#:752243-39-3| 6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide |
| S1195_Selleck |
| 2-Naphthalenecarboxamide, 6-(6,7-dihydro-7-hydroxy-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl- |
| TAK700 |
| (S)-6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-e]imidazol-7-yl)-N-methyl-2-naphthamide |
| TAK-700 (Orteronel) |
| 6-[7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthamide |
| Orteronel |
| TAK-700 |