CASIN

Modify Date: 2025-08-25 19:32:28

CASIN structure	Common Name	CASIN
	CAS Number	425399-05-9	Molecular Weight	306.401
	Density	1.2±0.1 g/cm3	Boiling Point	577.8±50.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₂₂N₂O	Melting Point	N/A
	MSDS	USA	Flash Point	303.3±30.1 °C

Use of CASIN

CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. In vitro: Treatment with CASIN (5 uM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells In vivo: Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs.

Name	CASIN
Synonym	More Synonyms

Description	CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM. In vitro: Treatment with CASIN (5 uM) reduced the elevated level of active Cdc42 observed in aged primitive hematopoietic cells to the level observed in young cells In vivo: Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Ras Research Areas >> Cancer
References	[1]. Florian MC et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30. [2]. Peterson JR et al. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Ras

Research Areas >> Cancer

References

[1]. Florian MC et al. Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30.

[2]. Peterson JR et al. Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.

Density	1.2±0.1 g/cm3
Boiling Point	577.8±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂N₂O
Molecular Weight	306.401
Flash Point	303.3±30.1 °C
Exact Mass	306.173218
LogP	3.60
Appearance of Characters	light yellow solid
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.682
Storage condition	-20℃

RIDADR	NONH for all modes of transport

Ethanol, 2-[(2,3,4,9-tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]-

2-[(6-Phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)amino]ethanol

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China
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China
Product Name: CASIN
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DC Chemicals Limited
China
Product Name: CASIN
Price: $500.0/100mg $850.0/250mg $1700.0/1g
Purity: 98.0%
Delivery: 3 Day
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Email: sales@dcchemicals.com

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Price: $92/10mM*1mLinDMSO

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CASIN

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.