NFAT Inhibitor-2

Modify Date: 2024-01-02 11:35:10

NFAT Inhibitor-2 Structure
NFAT Inhibitor-2 structure
Common Name NFAT Inhibitor-2
CAS Number 422546-87-0 Molecular Weight 446.47
Density N/A Boiling Point N/A
Molecular Formula C22H20F2N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NFAT Inhibitor-2


NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17)[1].

 Names

Name NFAT Inhibitor-2

 NFAT Inhibitor-2 Biological Activity

Description NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease, a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17)[1].
Related Catalog
References

[1]. Mercè PÉREZ RIBA, et al. Therapeutic uses of non-peptide inhibitors of the calcineurin - nfat signalling pathway. Patent WO2016207212A1.

 Chemical & Physical Properties

Molecular Formula C22H20F2N2O4S
Molecular Weight 446.47