Isaxonine
Modify Date: 2024-01-11 19:03:05
Isaxonine structure
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Common Name | Isaxonine | ||
|---|---|---|---|---|
| CAS Number | 4214-72-6 | Molecular Weight | 137.18200 | |
| Density | 1.065 g/cm3 | Boiling Point | 229.3ºC at 760mmHg | |
| Molecular Formula | C7H11N3 | Melting Point | 27-28ºC | |
| MSDS | N/A | Flash Point | 92.5ºC | |
Use of IsaxonineIsaxonine acts as a modifier of the surface pH of the bilayer[1]. Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery[2]. Isaxonine is a neurotrophic agent[3]. |
| Name | N-propan-2-ylpyrimidin-2-amine |
|---|---|
| Synonym | More Synonyms |
| Description | Isaxonine acts as a modifier of the surface pH of the bilayer[1]. Isaxonine accelerates the rate of peripheral nerve regeneration, stimulate axonal sprouting and promote motor and sensory function recovery[2]. Isaxonine is a neurotrophic agent[3]. |
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| Related Catalog | |
| In Vitro | Isaxonine has a favourable effect on nerve regeneration. After 8 weeks small type grouping is seen in rats receiving solvent only and large type grouping in rats treated with intraperitoneal Isaxonine. After 10 weeks a checkerboard pattern of the fibre types is observed in the muscles of animals receiving solvent only but fibre type grouping was present in those treated with Isaxonine. Isaxonine prevents synaptic remodelling by suppression of the redundant nerve endings from additional axons, which have regenerated more slowly, in making contact with motor endplates[4]. Isaxonine phosphate induces acute hepatitis which in most cases is reversible after withdrawal of the compound[5]. |
| References |
| Density | 1.065 g/cm3 |
|---|---|
| Boiling Point | 229.3ºC at 760mmHg |
| Melting Point | 27-28ºC |
| Molecular Formula | C7H11N3 |
| Molecular Weight | 137.18200 |
| Flash Point | 92.5ºC |
| Exact Mass | 137.09500 |
| PSA | 37.81000 |
| LogP | 1.36990 |
| Index of Refraction | 1.554 |
| HS Code | 2933599090 |
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|
~81%
Isaxonine CAS#:4214-72-6 |
| Literature: Ermolat'ev, Denis S.; Van Der Eycken, Erik V. Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6691 - 6697 |
|
~88%
Isaxonine CAS#:4214-72-6 |
| Literature: Steenackers, Hans P. L.; Ermolatev, Denis S.; Savaliya, Bharat; De Weerdt, Ami; De Coster, David; Shah, Anamik; Van Der Eycken, Erik V.; De Vos, Dirk E.; Vanderleyden, Jozef; De Keersmaecker, Sigrid C. J. Journal of Medicinal Chemistry, 2011 , vol. 54, # 2 p. 472 - 484 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| isopropylaminopyrimidine |
| 2-Pyrimidinamine,N-(1-methylethyl) |
| Isaxonine |
| Isaxonina |
| 2-(N-isopropylamino)pyrimidine |
| Isaxonina [INN-Spanish] |
| Isaxoninum |
| Isaxoninum [INN-Latin] |
| isopropyl(pyrimidin-2-yl)amine |
| 2-(ISOPROPYLAMINO)PYRIMIDINE |