Phenylpyropene C
Modify Date: 2025-09-02 18:01:12
Phenylpyropene C structure
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Common Name | Phenylpyropene C | ||
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| CAS Number | 419532-92-6 | Molecular Weight | 450.57 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H34O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Phenylpyropene CPhenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC50=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of acyl-CoA, with an IC50 of 16.0 μM[1][2]. |
| Name | S14-95 |
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| Synonym | More Synonyms |
| Description | Phenylpyropene C (S14-95), a JAK/STAT pathway inhibitor, can inhibit IFN-γ mediated expression of the reporter gene (IC50=5.4~10.8 μM). Phenylpyropene C also is an inhibitor of acyl-CoA, with an IC50 of 16.0 μM[1][2]. |
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| Related Catalog | |
| Target |
ACAT:16.0 μM (IC50) |
| In Vitro | Phenylpyropene C (0.1-1000 μM) inhibits ACAT activity with the IC50 of 16.0 μM in a dose dependent fashion[1]. Phenylpyropene C inhibits the IFN-γ mediated expression of the reporter gene with IC50s of 5.4 μM to approximately 10.8 μM[2]. Phenylpyropene C inhibits the expression of the proinflammatory enzymes COX-2 and NOS II at 10.8 μM in LPS/IFN-γ stimulated J774 mouse macrophages[2]. Phenylpyropene C inhibits the activation of the p38 MAP kinase, which is involved in the inducible expression of many proinflammatory genes[2]. |
| References |
| Molecular Formula | C28H34O5 |
|---|---|
| Molecular Weight | 450.57 |
| Hazard Codes | Xi |
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| Phenylpyropene C |