Lepadin H

Modify Date: 2025-08-25 13:36:31

Lepadin H structure	Common Name	Lepadin H
	CAS Number	412328-25-7	Molecular Weight	419.64
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₄₅NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Lepadin H

Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway[1].

Name	Lepadin H

Description	Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Apoptosis >> Ferroptosis
References	[1]. Wang W, et al. Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy. J Med Chem. 2023 Aug 24;66(16):11201-11215.

Molecular Formula	C₂₆H₄₅NO₃
Molecular Weight	419.64

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Lepadin H

Use of Lepadin H

Names

Lepadin H Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.