Taxiresinol structure
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Common Name | Taxiresinol | ||
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| CAS Number | 40951-69-7 | Molecular Weight | 346.37 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 590.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H22O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 310.8±30.1 °C | |
Use of TaxiresinolTaxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1]. |
| Name | 4-[4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)oxolan-2-yl]benzene-1,2-diol |
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| Synonym | More Synonyms |
| Description | Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1]. |
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| Related Catalog | |
| In Vivo | Taxiresinol (100 mg/kg,口服,一次) 对对苯醌(p-benzoquinone)诱导的小鼠腹部收缩表现出显著的镇痛作用[1]。 Animal Model: Male Swiss albino mice (20-25 g)[1] Dosage: 100 mg/kg Administration: Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O. Result: Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 590.3±50.0 °C at 760 mmHg |
| Molecular Formula | C19H22O6 |
| Molecular Weight | 346.37 |
| Flash Point | 310.8±30.1 °C |
| Exact Mass | 346.141632 |
| PSA | 99.38000 |
| LogP | 1.33 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.627 |
| InChIKey | SNZZAHRDXCGWEM-LPMFXHHGSA-N |
| SMILES | COc1cc(CC2COC(c3ccc(O)c(O)c3)C2CO)ccc1O |
| Hazard Codes | Xi |
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| 1,2-Benzenediol, 4-[(2S,3R,4R)-tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)-2-furanyl]- |
| 4-[(2S,3R,4R)-4-(4-Hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydro-2-furanyl]-1,2-benzenediol |