2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide

Modify Date: 2024-01-03 10:20:41

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure
2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide structure
Common Name 2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide
CAS Number 407-24-9 Molecular Weight 209.047
Density 1.6±0.1 g/cm3 Boiling Point 89.1±40.0 °C at 760 mmHg
Molecular Formula C4HF6NO2 Melting Point 80-86 °C
MSDS Chinese USA Flash Point 7.7±27.3 °C

 Names

Name 2,2,2-trifluoro-N-(2,2,2-trifluoroacetyl)acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 89.1±40.0 °C at 760 mmHg
Melting Point 80-86 °C
Molecular Formula C4HF6NO2
Molecular Weight 209.047
Flash Point 7.7±27.3 °C
Exact Mass 208.991150
PSA 46.17000
LogP 1.43
Vapour Pressure 59.4±0.2 mmHg at 25°C
Index of Refraction 1.310

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes C
Risk Phrases 36/37/38
Safety Phrases S26-S36/37/39
RIDADR UN 3261 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8

 Synthetic Route

~57%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

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CAS#:407-24-9

Literature: Tanaka, Chiaki; Nasu, Keiko; Yamamoto, Noriko; Shibata, Megumi Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 9 p. 3374 - 3376

~10%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

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CAS#:407-24-9

Detail
Literature: Polivin, Yu. N.; Ageev, E. A. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 1.2 p. 178 - 180 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , # 1 p. 195 - 198

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2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Literature: Young,J.A. et al. Journal of the American Chemical Society, 1960 , vol. 82, p. 4553 - 4556

~32%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Literature: Kiemstedt, Wolfgang; Sundermeyer, Wolfgang Chemische Berichte, 1982 , vol. 115, # 3 p. 919 - 925

~10%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Detail
Literature: Polivin, Yu. N.; Ageev, E. A. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1991 , vol. 40, # 1.2 p. 178 - 180 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1991 , # 1 p. 195 - 198

~25%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Detail
Literature: Polivin, Yu. N.; Vinokurov, V. A.; Karakhanov, R. A.; Silin, M. A.; Ageev, E. A.; Tagavov, I. T. Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 10 p. 1832 - 1834 Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 10 p. 2072 - 2074

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2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Literature: Gmelin Handbook: F: PerFHalOrg.SVol.3, 6.2.3.4, page 152 - 186

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2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Literature: Minnesota Mining and Mfg.Co. Patent: US2701814 , 1953 ;

~%

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide Structure

2,2,2-Trifluoro...

CAS#:407-24-9

Literature: Ye; Noftle Journal of Fluorine Chemistry, 1997 , vol. 81, # 2 p. 193 - 196

 Articles3

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Derivatization procedures for gas chromatographic-mass spectrometric determination of xenobiotics in biological samples, with special attention to drugs of abuse and doping agents.

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 Synonyms

2,2,2-Trifluoro-N-(trifluoroacetyl)acetamide
bistrifluoroacetamide
Bis-trifluoracetyl-amin
EINECS 206-981-3
Acetamide, 2,2,2-trifluoro-N-(2,2,2-trifluoroacetyl)-
bis-trifluoroacetyl-amine
MFCD00013564