MSX-130

Modify Date: 2024-01-10 20:01:50

MSX-130 Structure
MSX-130 structure
Common Name MSX-130
CAS Number 4051-59-6 Molecular Weight 514.618
Density 1.2±0.1 g/cm3 Boiling Point 766.3±48.0 °C at 760 mmHg
Molecular Formula C36H26N4 Melting Point N/A
MSDS N/A Flash Point 326.5±22.5 °C

 Use of MSX-130


MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].

 Names

Name 2,2'-(1,4-Phenylene)bis(4,5-diphenyl-1H-imidazole)
Synonym More Synonyms

 MSX-130 Biological Activity

Description MSX-130 is a CXCR4 antagonist. MSX-130 inhibits cancer metastasis[1].
Related Catalog
Target

CXCR4

In Vitro The C-X-C chemokine receptor-4 (CXCR4) is a seven trans-membrane G-protein coupled receptor (GPCR) classified as a member of the family I GPCR or rhodopsin-like GPCR family. CXCR4 plays an important role in cancer metastasis, regulation of stem cell trafficking, and neovascularization[1].
References

[1]. Zhan W, et al. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 766.3±48.0 °C at 760 mmHg
Molecular Formula C36H26N4
Molecular Weight 514.618
Flash Point 326.5±22.5 °C
Exact Mass 514.215759
LogP 11.84
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.672

 Synonyms

2,2'-(1,4-Phenylene)bis(4,5-diphenyl-1H-imidazole)
2,2'-benzene-1,4-diylbis(4,5-diphenyl-1H-imidazole)
1H-Imidazole, 2,2'-(1,4-phenylene)bis[4,5-diphenyl-