Taribavirin hydrochloride
Modify Date: 2024-01-07 10:37:08
Taribavirin hydrochloride structure
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Common Name | Taribavirin hydrochloride | ||
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| CAS Number | 40372-00-7 | Molecular Weight | 279.68100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H14ClN5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Taribavirin hydrochlorideTaribavirin hydrochloride is an inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus[1]. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia[2]. |
| Name | 1-[(2R,3S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide,hydrochloride |
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| Synonym | More Synonyms |
| Description | Taribavirin hydrochloride is an inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus[1]. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia[2]. |
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| Related Catalog | |
| Target |
Inosine monophosphate dehydrogenase[1] |
| In Vitro | Taribavirin hydrochloride (0-2 μM; 24 hours) significantly induces MCF-7 cell death, recording half inhibitory effect (IC50) of 0.756 μM in MCF-7 cells[1]. Cell Viability Assay[1] Cell Line: MCF-7 cells Concentration: 0 μM, 0.1 μM, 1 μM, 2 μM Incubation Time: 24 hours Result: Decreased MCF-7 cell growth. |
| References |
| Molecular Formula | C8H14ClN5O4 |
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| Molecular Weight | 279.68100 |
| Exact Mass | 279.07300 |
| PSA | 150.50000 |
| Precursor 0 | |
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| DownStream 1 | |
CAS#:36791-04-5| Ribamidine hydrochloride |
| Viramidine hydrochloride |
| 1-|A-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboximidamide Monohydrochloride |
| AVS 206 |