Ceftaroline fosamil acetate
Modify Date: 2024-01-02 12:10:50
Ceftaroline fosamil acetate structure
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Common Name | Ceftaroline fosamil acetate | ||
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| CAS Number | 400827-55-6 | Molecular Weight | 762.752 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H27N8O11PS4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ceftaroline fosamil acetateCeftaroline fosamil hydrate acetate is a potent cephalosporin antibiotic. Ceftaroline fosamil hydrate acetate shows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate acetate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP)[1][2][3]. |
| Name | ceftaroline fosamil acetate monohydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Ceftaroline fosamil hydrate acetate is a potent cephalosporin antibiotic. Ceftaroline fosamil hydrate acetate shows broad-spectrum activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae, and common Gram-negative organisms. Ceftaroline fosamil hydrate acetate has anti-infective activity, and can be used for the research of complicated skin and skin structure infections (cSSSIs) and community-acquired bacterial pneumonia (CABP)[1][2][3]. |
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| Related Catalog | |
| In Vivo | Ceftaroline fosamil hydrate acetate (s.c.) shows protective effects against experimental systemic infection caused by S. aureus N133 in mice, with ED50s of 1.60-2.37 mg/kg[1]. Ceftaroline fosamil hydrate acetate (10 mg/kg; s.c.) disappeares rapidly and converts smoothly into T-91825 in blood of rats and monkeys[1]. |
| References |
| Molecular Formula | C24H27N8O11PS4 |
|---|---|
| Molecular Weight | 762.752 |
| Exact Mass | 762.041992 |
| PSA | 393.38000 |
| LogP | 1.88460 |
| ceftaroline fosamil acetate monohydrate |
| (6R,7R)-7-({(2Z)-2-(Ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl}amino)-3-{[4-(1-methyl-4-pyridiniumyl)-1,3-thiazol-2-yl]sulfanyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate acetate hydrate (1:1:1) |
| Ceftaroline fosamil acetate hydrate |
| (6R,7R)-7-[[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,acetate,hydrate |
| Ceftaroline fosamil acetate |