2,5-Dibromo-6-methylpyridine

Modify Date: 2024-01-03 17:02:40

2,5-Dibromo-6-methylpyridine Structure
2,5-Dibromo-6-methylpyridine structure
Common Name 2,5-Dibromo-6-methylpyridine
CAS Number 39919-65-8 Molecular Weight 250.92
Density 1.9±0.1 g/cm3 Boiling Point 243.9±35.0 °C at 760 mmHg
Molecular Formula C6H5Br2N Melting Point 0°C
MSDS Chinese USA Flash Point 101.3±25.9 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Use of 2,5-Dibromo-6-methylpyridine


2,5-Dibromo-6-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 2,5-dibromo-6-methylpyridine
Synonym More Synonyms

 2,5-Dibromo-6-methylpyridine Biological Activity

Description 2,5-Dibromo-6-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 243.9±35.0 °C at 760 mmHg
Melting Point 0°C
Molecular Formula C6H5Br2N
Molecular Weight 250.92
Flash Point 101.3±25.9 °C
Exact Mass 248.878860
PSA 12.89000
LogP 3.04
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.594

 MSDS

3,6-Dibromo-2-methylpyridine Revision number: 5.3
SAFETY DATA SHEET

Section1. IDENTIFICATION
Product name:3,6-Dibromo-2-methylpyridine

Revision number:5.3

Section2. HAZARDS IDENTIFICATION
GHS classification
PHYSICAL HAZARDSNot classified
HEALTH HAZARDS
Acute toxicity (Oral)Category 4
Category 2
Skin corrosion/irritation
Serious eye damage/eye irritationCategory 2A
Not classified
ENVIRONMENTAL HAZARDS
GHS label elements, including precautionary statements
Pictograms or hazard symbols
Signal wordWarning
Hazard statementsHarmful if swallowed
Causes skin irritation
Causes serious eye irritation
Precautionary statements:
Do not eat, drink or smoke when using this product.
[Prevention]
Wash hands thoroughly after handling.
Wear protective gloves/eye protection/face protection.
[Response]IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Rinse mouth.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing.
If eye irritation persists: Get medical advice/attention.
IF ON SKIN: Gently wash with plenty of soap and water.
If skin irritation occurs: Get medical advice/attention.
Take off contaminated clothing and wash before reuse.
[Disposal]Dispose of contents/container through a waste management company authorized by
the local government.

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance/mixture:Substance
Components:3,6-Dibromo-2-methylpyridine
>98.0%(GC)(T)
Percent:
CAS Number:39919-65-8
3,6-Dibromo-2-methylpyridine

Section3. COMPOSITION/INFORMATION ON INGREDIENTS
Synonyms:3,6-Dibromo-2-picoline
Chemical Formula:C6H5Br2N

Section4. FIRST AID MEASURES
Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Inhalation:
Get medical advice/attention if you feel unwell.
Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
Skin contact:
soap and water. If skin irritation or rash occurs: Get medical advice/attention.
Rinse cautiously with water for several minutes. Remove contact lenses, if present
Eye contact:
and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Ingestion:Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air-
tight goggles.

Section5. FIRE-FIGHTING MEASURES
Suitable extinguishingDry chemical, foam, water spray, carbon dioxide.
media:
Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to
generate poisonous fume.
from the chemical:
Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
method according to the surrounding situation is used. Uninvolved persons should
evacuate to a safe place. In case of fire in the surroundings: Remove movable
containers if safe to do so.
Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment.
equipment for firefighters:

Section6. ACCIDENTAL RELEASE MEASURES
Use personal protective equipment. Keep people away from and upwind of spill/leak.
Personal precautions,
protective equipment and Entry to non-involved personnel should be controlled around the leakage area by
emergency procedures: roping off, etc.
Environmental precautions: Prevent product from entering drains.
Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
up: appropriate laws and regulations.

Section7. HANDLING AND STORAGE
Precautions for safe handling
Handling is performed in a well ventilated place. Wear suitable protective equipment.
Technical measures:
Prevent dispersion of dust. Wash hands and face thoroughly after handling.
Use a local exhaust if dust or aerosol will be generated.
Advice on safe handling: Avoid contact with skin, eyes and clothing.
Conditions for safe storage, including any
incompatibilities
Storage conditions:Keep container tightly closed. Store in a cool and dark place.
Store away from incompatible materials such as oxidizing agents.
Packaging material:Comply with laws.

Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Install a closed system or local exhaust as possible so that workers should not be
Engineering controls:
exposed directly. Also install safety shower and eye bath.
Personal protective equipment
Respiratory protection: Dust respirator. Follow local and national regulations.
Hand protection:Protective gloves.
Eye protection:Safety glasses. A face-shield, if the situation requires.
Skin and body protection: Protective clothing. Protective boots, if the situation requires.
3,6-Dibromo-2-methylpyridine

Section9. PHYSICAL AND CHEMICAL PROPERTIES
Physical state (20°C):Solid
Crystal- Powder
Form:
Colour:Very pale yellow - Pale yellow
No data available
Odour:
pH: No data available
Melting point/freezing point:38°C
Boiling point/range:No data available
No data available
Flash point:
Flammability or explosive
limits:
Lower:No data available
No data available
Upper:
Relative density:No data available
Solubility(ies):
[Water]No data available
[Other solvents]
Soluble:Methanol
2.89
Log Pow:

Section10. STABILITY AND REACTIVITY
Chemical stability:Stable under proper conditions.
Possibility of hazardous No special reactivity has been reported.
reactions:
Incompatible materials: Oxidizing agents
Hazardous decomposition Carbon monoxide, Carbon dioxide, Nitrogen oxides (NOx), Hydrogen bromide
products:

Section11. TOXICOLOGICAL INFORMATION
No data available
Acute Toxicity:
Skin corrosion/irritation: No data available
No data available
Serious eye
damage/irritation:
Germ cell mutagenicity: No data available
Carcinogenicity:
No data available
IARC =
NTP =No data available
No data available
Reproductive toxicity:

Section12. ECOLOGICAL INFORMATION
Ecotoxicity:
Fish:No data available
Crustacea:No data available
Algae:No data available
Persistence / degradability: No data available
BioaccumulativeNo data available
potential(BCF):
Mobility in soil
Log Pow:2.89
Soil adsorption (Koc):No data available
Henry's LawNo data available
constant(PaM3/mol):
3,6-Dibromo-2-methylpyridine

Section13. DISPOSAL CONSIDERATIONS
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
Observe all federal, state and local regulations when disposing of the substance.

Section14. TRANSPORT INFORMATION
Hazards Class:Does not correspond to the classification standard of the United Nations
UN-No:Not listed

Section15. REGULATORY INFORMATION
Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
loading and unloading were prescribed.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H318
Precautionary Statements P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi,Xn
Risk Phrases R22
Safety Phrases S26-S36/37/39
RIDADR UN 2811 6.1/PG 3
Packaging Group III
HS Code 2933399090

 Synthetic Route

~73%

2,5-Dibromo-6-methylpyridine Structure

2,5-Dibromo-6-m...

CAS#:39919-65-8

Literature: ANORMED INC. Patent: WO2007/22371 A2, 2007 ; Location in patent: Page/Page column 50-51 ; WO 2007/022371 A2

~77%

2,5-Dibromo-6-methylpyridine Structure

2,5-Dibromo-6-m...

CAS#:39919-65-8

Literature: BRISTOL-MYERS SQUIBB PHARMA COMPANY Patent: WO2005/51954 A2, 2005 ; Location in patent: Page/Page column 38; 39 ; WO 2005/051954 A2

~70%

2,5-Dibromo-6-methylpyridine Structure

2,5-Dibromo-6-m...

CAS#:39919-65-8

Literature: BRISTOL-MYERS SQUIBB PHARMA COMPANY Patent: WO2005/51954 A2, 2005 ; Location in patent: Page/Page column 38; 39 ; WO 2005/051954 A2

~%

2,5-Dibromo-6-methylpyridine Structure

2,5-Dibromo-6-m...

CAS#:39919-65-8

Literature: Diaz, Caroline Jean; Haffner, Curt Dale; Speake, Jason Daniel; Zhang, Cunyu; Mills, Wendy Yoon; Spearing, Paul Kenneth; Cowan, David John; Green, Gary Martin Patent: US2010/222345 A1, 2010 ; Location in patent: Page/Page column 95 ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Pyridine, 3,6-dibromo-2-methyl-
2,5-DIBROMO-6-METHYLPYRIDINE
3,6-Dibromo-2-methylpyridine
MFCD06254589
3,6-Dibromo-2-picoline