Asperosaponin VI

Modify Date: 2024-01-02 15:01:10

Asperosaponin VI Structure
Asperosaponin VI structure
Common Name Asperosaponin VI
CAS Number 39524-08-8 Molecular Weight 929.096
Density 1.43 Boiling Point 990.2±65.0 °C at 760 mmHg
Molecular Formula C47H76O18 Melting Point N/A
MSDS N/A Flash Point 282.1±27.8 °C

 Use of Asperosaponin VI


Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].

 Names

Name Akebia saponin D
Synonym More Synonyms

 Asperosaponin VI Biological Activity

Description Asperosaponin VI, A saponin component from Dipsacus asper wall, induces osteoblast differentiation through BMP‐2/p38 and ERK1/2 pathway[1]. Asperosaponin Ⅵ inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB[2].
Related Catalog
References

[1]. Niu Y, et al. Asperosaponin VI, a saponin component from Dipsacus asper wall, induces osteoblast differentiation through bone morphogenetic protein-2/p38 and extracellular signal-regulated kinase 1/2 pathway. Phytother Res. 2011 Nov;25(11):1700-6.

[2]. Li C, et al. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010 Dec 15;649(1-3):100-7.

 Chemical & Physical Properties

Density 1.43
Boiling Point 990.2±65.0 °C at 760 mmHg
Molecular Formula C47H76O18
Molecular Weight 929.096
Flash Point 282.1±27.8 °C
Exact Mass 928.503174
PSA 294.98000
LogP 4.18
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.627

 Safety Information

Hazard Codes Xi
Safety Phrases 24/25
HS Code 29389090

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

3-O-(triphenylmethyl)prop-1-yn-3-ol
Asperosaponin
D-Glucopyranose, 1-O-[(5ξ,8ξ,9ξ,10ξ,17ξ,18ξ)-3-(α-L-arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-
1-O-[(5ξ,8ξ,9ξ,10ξ,17ξ,18ξ)-3-(α-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-D-glucopyranose
Asperosaponin VI
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