5’-Azido-5’-deoxyuridine

Modify Date: 2024-09-07 13:11:02

5’-Azido-5’-deoxyuridine Structure
5’-Azido-5’-deoxyuridine structure
Common Name 5’-Azido-5’-deoxyuridine
CAS Number 39483-48-2 Molecular Weight 269.21
Density N/A Boiling Point N/A
Molecular Formula C9H11N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5’-Azido-5’-deoxyuridine


5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-(5-Azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
Synonym More Synonyms

 5’-Azido-5’-deoxyuridine Biological Activity

Description 5’-Azido-5’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H11N5O5
Molecular Weight 269.21
Exact Mass 269.076019
LogP -1.46

 Synonyms

1-(5-Azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 1-(5-azido-5-deoxy-β-D-ribofuranosyl)-4-hydroxy-
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