CAY10760
Modify Date: 2025-09-26 19:33:49
CAY10760 structure
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Common Name | CAY10760 | ||
|---|---|---|---|---|
| CAS Number | 391889-85-3 | Molecular Weight | 485.961 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C28H24ClN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CAY10760Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor (EC50=19 μM). Homologous recombination-IN-1 can interfere with homologous recombination[1]. |
| Name | CAY10760 |
|---|---|
| Synonym | More Synonyms |
| Description | Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor (EC50=19 μM). Homologous recombination-IN-1 can interfere with homologous recombination[1]. |
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| Related Catalog | |
| In Vitro | Homologous recombination-IN-1 (10-40 μM; 5 h) reduces cell homologous recombination in a dose-dependent manner[1]. Western Blot Analysis[1] Cell Line: BxPC3 cells Concentration: 10-40 μM Incubation Time: 5 hours Result: Led to homologous recombination inhibition with an EC50 value of 18.4 μM. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H24ClN3O3 |
| Molecular Weight | 485.961 |
| Exact Mass | 485.150604 |
| LogP | 4.39 |
| Index of Refraction | 1.660 |
| InChIKey | LAVOKBSCOSIGER-UHFFFAOYSA-N |
| SMILES | CCC(=O)N1N=C(c2c(-c3ccccc3)c3cc(Cl)ccc3[nH]c2=O)CC1c1ccc(OC)cc1 |
| 2(1H)-Quinolinone, 6-chloro-3-[4,5-dihydro-5-(4-methoxyphenyl)-1-(1-oxopropyl)-1H-pyrazol-3-yl]-4-phenyl- |
| CAY10760 |
| 6-Chloro-3-[5-(4-methoxyphenyl)-1-propionyl-4,5-dihydro-1H-pyrazol-3-yl]-4-phenyl-2(1H)-quinolinone |