(R)?-?PIA
(R)?-?PIA structure
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Common Name | (R)?-?PIA | ||
|---|---|---|---|---|
| CAS Number | 38594-96-6 | Molecular Weight | 385.42 | |
| Density | 1.506g/cm3 | Boiling Point | 675.716ºC at 760 mmHg | |
| Molecular Formula | C19H23N5O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 362.46ºC | |
Use of (R)?-?PIA(-)-N6-phenylisopropyl adenosine (D-phenylisopropyladenosine) is a adenosine receptor agonist. (-)-N6-phenylisopropyl adenosine inhibits K+-evoked Ca2+ uptake with an IC50 value of 0.5 µM[1]. |
| Name | ()-N6-(2-Phenylisopropyl)adenosine |
|---|---|
| Synonym | More Synonyms |
| Description | (-)-N6-phenylisopropyl adenosine (D-phenylisopropyladenosine) is a adenosine receptor agonist. (-)-N6-phenylisopropyl adenosine inhibits K+-evoked Ca2+ uptake with an IC50 value of 0.5 µM[1]. |
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| Related Catalog | |
| References |
| Density | 1.506g/cm3 |
|---|---|
| Boiling Point | 675.716ºC at 760 mmHg |
| Molecular Formula | C19H23N5O4 |
| Molecular Weight | 385.42 |
| Flash Point | 362.46ºC |
| Exact Mass | 385.17500 |
| PSA | 125.55000 |
| LogP | 0.55390 |
| Index of Refraction | 1.712 |
| InChIKey | RIRGCFBBHQEQQH-SSFGXONLSA-N |
| SMILES | CC(Cc1ccccc1)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.
Mol. Pharmacol. 29 , 331, (1986) [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuronamide) is known to bind to both the A1 and A2 subtypes of adenosine receptor in rat striatal membranes. In order to study the putati... |
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Negative crosstalk between M1 and M2 muscarinic autoreceptors involves endogenous adenosine activating A1 receptors at the rat motor endplate.
Neurosci. Lett. 459 , 127-131, (2009) At the rat motor nerve terminals, activation of muscarinic M(1) receptors negatively modulates the activity of inhibitory muscarinic M(2) receptors. The present work was designed to investigate if the... |
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Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors.
J. Pharmacol. Exp. Ther. 322(1) , 332-40, (2007) The inactivation of synaptic serotonin (5-hydroxytryptamine, 5-HT) is largely established through the actions of the presynaptic, antidepressant-sensitive 5-HT transporter (SERT, SLC6A4). Recent studi... |
| (R)-N6-(1-Methyl-2-phenylethyl)adenosine N6-(L-2-Phenylisopropyl)adenosine R-(−)-PIA |
| EINECS 254-028-5 |
| (−)-N6-(2-Phenylisopropyl)adenosine |
| MFCD00069194 |
| (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(2R)-1-phenylpropan-2-yl]amino]purin-9-yl]oxolane-3,4-diol |