D75-4590

Modify Date: 2025-08-20 13:02:29

D75-4590 Structure
D75-4590 structure
Common Name D75-4590
CAS Number 384376-42-5 Molecular Weight 349.47
Density 1.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C21H27N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of D75-4590


D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity[1].

 Names

Name D75-4590
Synonym More Synonyms

 D75-4590 Biological Activity

Description D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity[1].
Related Catalog
In Vitro D75-4590 has activities against a variety of Candida species, including fluconazole-resistant strains. Most strains of C. albicans, C. tropicalis, and C. parapsilosis displayed trailing growth phenomena similar to those observed in the presence of azoles[1].
References

[1]. Akihiro Kitamura, et al. Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis. Antimicrob Agents Chemother. 2009 Feb;53(2):670-7.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Molecular Formula C21H27N5
Molecular Weight 349.47
Exact Mass 349.226654
LogP 4.26
Index of Refraction 1.607

 Synonyms

1-{[2-(Diethylamino)ethyl]amino}-2-ethyl-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
D75-4590
MFCD05738885
Pyrido[1,2-a]benzimidazole-4-carbonitrile, 1-[[2-(diethylamino)ethyl]amino]-2-ethyl-3-methyl-
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