aloenin a

Modify Date: 2024-01-09 12:21:58

aloenin a structure	Common Name	aloenin a
	CAS Number	38412-46-3	Molecular Weight	410.372
	Density	1.6±0.1 g/cm3	Boiling Point	787.8±60.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₂O₁₀	Melting Point	145℃
	MSDS	Chinese USA	Flash Point	282.2±26.4 °C

Use of aloenin a

Aloenin (Aloenin A) is a class of anthraquinones isolated from Aloe arborescens. Aloenin has potent peroxyl radical-scavenging activities and moderate inhibitory active on β-secretase (BACE)[1][2].

Name	6-[4-hydroxy-2-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-4-methoxypyran-2-one
Synonym	More Synonyms

Description	Aloenin (Aloenin A) is a class of anthraquinones isolated from Aloe arborescens. Aloenin has potent peroxyl radical-scavenging activities and moderate inhibitory active on β-secretase (BACE)[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Beta-secretase Research Areas >> Neurological Disease
References	[1]. Sun YN, et al. Antioxidant and anti-osteoporotic effects of anthraquinones and related constituents from the aqueous dissolved Aloe exudates. Nat Prod Res. 2017 Dec;31(23):2810-2813. [2]. Gao B, et al. Active constituents from Aloe arborescens as BACE inhibitors. Yao Xue Xue Bao. 2006 Oct;41(10):1000-3.

Description

Aloenin (Aloenin A) is a class of anthraquinones isolated from Aloe arborescens. Aloenin has potent peroxyl radical-scavenging activities and moderate inhibitory active on β-secretase (BACE)[1][2].

Related Catalog

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

References

[1]. Sun YN, et al. Antioxidant and anti-osteoporotic effects of anthraquinones and related constituents from the aqueous dissolved Aloe exudates. Nat Prod Res. 2017 Dec;31(23):2810-2813.

[2]. Gao B, et al. Active constituents from Aloe arborescens as BACE inhibitors. Yao Xue Xue Bao. 2006 Oct;41(10):1000-3.

Density	1.6±0.1 g/cm3
Boiling Point	787.8±60.0 °C at 760 mmHg
Melting Point	145℃
Molecular Formula	C₁₉H₂₂O₁₀
Molecular Weight	410.372
Flash Point	282.2±26.4 °C
Exact Mass	410.121307
PSA	159.05000
LogP	-0.48
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.663
Storage condition	?20°C

aloenin a MSDS(Chinese)

RIDADR	NONH for all modes of transport

Precursor 0
DownStream 2
CAS#:2280-44-6 D-glucopyranose CAS#:59163-53-0 Aloenin aglycone

The content of secondary phenol metabolites in pruned leaves of Aloe arborescens, a comparison between two methods: leaf exudates and leaf water extract.

J. Nat. Med. 62(4) , 430-5, (2008)

Aloe arborescens plants, originating from the deserts of South Africa, are grown in the Introduction Garden at Sede Boker in the Negev Desert of Israel. In previous studies, we developed agro-technica...

Determination of aloenin, barbaloin and isobarbaloin in aloe species by micellar electrokinetic chromatography.

J. Chromatogr. B. Biomed. Sci. Appl. 752(1) , 91-7, (2001)

Aloenin, barbaloin and isobarbaloin in JP Aloe, Aloe barbadensis (Aloe vera) and Aloe arborescens Miller var. natalensis Berger (Aloe arborescens Miller) were determined by micellar electrokinetic chr...

Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.

J. Ethnopharmacol. 103(3) , 468-77, (2006)

We carried out three experimental trials to determine antidiabetic effects of Aloe arborescens Miller components. Firstly, ICR mice which received frequent injections of streptozotocin (Sz) in small d...

2H-Pyran-2-one, 6-[2-(β-D-glucopyranosyloxy)-4-hydroxy-6-methylphenyl]-4-methoxy-

Aloenin A

5-Hydroxy-2-(4-methoxy-2-oxo-2H-pyran-6-yl)-3-methylphenyl β-D-glucopyranoside

Aloenin

2H-Pyran-2-one, 6-(2-(β-D-glucopyranosyloxy)-4-hydroxy-6-methylphenyl)-4-methoxy-