(+)-Penbutolol
Modify Date: 2025-08-26 10:29:17
(+)-Penbutolol structure
|
Common Name | (+)-Penbutolol | ||
|---|---|---|---|---|
| CAS Number | 38363-41-6 | Molecular Weight | 291.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H29NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (+)-Penbutolol(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2]. |
| Name | (+)-Penbutolol |
|---|
| Description | (+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.74 μM (β-adrenoceptor)[1]. |
| In Vitro | (+)-penbutolol on the [Ca2+]i-increase induced by LPC is concentration-dependent[1]. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively)[2]. |
| References |
| Molecular Formula | C18H29NO2 |
|---|---|
| Molecular Weight | 291.43 |
| InChIKey | KQXKVJAGOJTNJS-OAHLLOKOSA-N |
| SMILES | CC(C)(C)NCC(O)COc1ccccc1C1CCCC1 |