38363-41-6
38363-41-6 structure
- Name: (+)-Penbutolol
- Chemical Name: (+)-Penbutolol
- CAS Number: 38363-41-6
- Molecular Formula: C18H29NO2
- Molecular Weight: 291.43
- Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
- Create Date: 2019-02-09 10:07:56
- Modify Date: 2024-01-17 19:01:15
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(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2].
| Name | (+)-Penbutolol |
|---|
| Description | (+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.74 μM (β-adrenoceptor)[1]. |
| In Vitro | (+)-penbutolol on the [Ca2+]i-increase induced by LPC is concentration-dependent[1]. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively)[2]. |
| References |
| Molecular Formula | C18H29NO2 |
|---|---|
| Molecular Weight | 291.43 |