N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE

Modify Date: 2025-09-26 13:12:13

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure
N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE structure
 Common Name N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE
CAS Number 379230-38-3 Molecular Weight 417.818
Density 1.5±0.1 g/cm3 Boiling Point 525.2±50.0 °C at 760 mmHg
Molecular Formula C20H17ClFN3O4 Melting Point N/A
MSDS N/A Flash Point 271.5±30.1 °C

 Names

Name N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(oxan-4-yloxy)quinazolin-4-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 525.2±50.0 °C at 760 mmHg
Molecular Formula C20H17ClFN3O4
Molecular Weight 417.818
Flash Point 271.5±30.1 °C
Exact Mass 417.089172
PSA 74.73000
LogP 3.50
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.674

 Safety Information

HS Code 2934999090

 Synthetic Route

Tetrahydro-4-pyranol structure

Tetrahydro-4-pyranol

CAS#:2081-44-9

N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-5,7-difluoroquinazolin-4-amine structure

N-(5-Chlorobenz...

CAS#:893428-69-8

~81%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692
Tetrahydro-4-pyranol structure

Tetrahydro-4-pyranol

CAS#:2081-44-9

5,7-difluoro-N-(5-chloro-1,3-benzodioxol-4-yl)quinazolin-4-amine hydrochloride structure

5,7-difluoro-N-...

CAS#:893428-68-7

~77%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093
5,7-difluoro-N-(5-chloro-1,3-benzodioxol-4-yl)quinazolin-4-amine hydrochloride structure

5,7-difluoro-N-...

CAS#:893428-68-7

~%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 57 ; WO 2006/064217 A2
4-chloro-7-fluoro-5-tetrahydropyran-4-yloxyquinazoline structure

4-chloro-7-fluo...

CAS#:379228-55-4

5-chloro-1,3-benzodioxol-4-amine structure

5-chloro-1,3-be...

CAS#:379228-45-2

~%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 56-57 ; WO 2006/064217 A2
5,7-Difluoroquinazolin-4(3H)-one structure

5,7-Difluoroqui...

CAS#:379228-58-7

~%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093
4-Chloro-5,7-difluoroquinazoline structure

4-Chloro-5,7-di...

CAS#:791602-75-0

~%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692
5-chloro-1,3-benzodioxol-4-amine structure

5-chloro-1,3-be...

CAS#:379228-45-2

~%

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE Structure

N-(5-CHLOROBENZ...

CAS#:379230-38-3

Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-[(tetrahydro-2H-pyran-4-yl)oxy]-
N-(5-Chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinamine
N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-7-fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-amine
7-fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
4-(6-chloro-2,3-methylenedioxyanilino)-7-fluoro-5-tetrahydropyran-4-yloxyquinazoline
QC-8392
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N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE suppliers

N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE price

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Chemsrc provides CAS#:379230-38-3 MSDS, density, melting point, boiling point, structure, etc. Its name is N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE>> amp version: N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE

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