379230-38-3
379230-38-3 structure
- Name: N-(5-CHLOROBENZO[D][1,3]DIOXOL-4-YL)-7-FLUORO-5-((TETRAHYDRO-2H-PYRAN-4-YL)OXY)QUINAZOLIN-4-AMINE
- Chemical Name: N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(oxan-4-yloxy)quinazolin-4-amine
- CAS Number: 379230-38-3
- Molecular Formula: C20H17ClFN3O4
- Molecular Weight: 417.818
- Create Date: 2018-12-29 19:37:09
- Modify Date: 2025-09-26 13:12:13
| Name | N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(oxan-4-yloxy)quinazolin-4-amine |
|---|---|
| Synonyms |
4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-[(tetrahydro-2H-pyran-4-yl)oxy]-
N-(5-Chloro-1,3-benzodioxol-4-yl)-7-fluoro-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinamine N-(5-Chlorobenzo[d][1,3]dioxol-4-yl)-7-fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazolin-4-amine 7-fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine 4-(6-chloro-2,3-methylenedioxyanilino)-7-fluoro-5-tetrahydropyran-4-yloxyquinazoline QC-8392 |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 525.2±50.0 °C at 760 mmHg |
| Molecular Formula | C20H17ClFN3O4 |
| Molecular Weight | 417.818 |
| Flash Point | 271.5±30.1 °C |
| Exact Mass | 417.089172 |
| PSA | 74.73000 |
| LogP | 3.50 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.674 |
| HS Code | 2934999090 |
|---|
|
~81%
379230-38-3 |
| Literature: Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692 |
|
~77%
379230-38-3 |
| Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093 |
|
~%
379230-38-3 |
| Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 57 ; WO 2006/064217 A2 |
|
~%
379230-38-3 |
| Literature: ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2006/64217 A2, 2006 ; Location in patent: Page/Page column 56-57 ; WO 2006/064217 A2 |
|
~%
379230-38-3 |
| Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093 |
|
~%
379230-38-3 |
| Literature: Raw, Steven A.; Taylor, Brian A.; Tomasi, Simone Organic Process Research and Development, 2011 , vol. 15, # 3 p. 688 - 692 |
|
~%
379230-38-3 |
| Literature: Ford, J. Gair; OKearney-Mcmullan, Anne; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Purdie, Mark; Withnall, Jane; Frances Wood, Phil OKeefe Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1088 - 1093 |
| Precursor 5 | |
|---|---|
| DownStream 0 | |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |