UNC10201652
Modify Date: 2024-04-03 08:10:37
UNC10201652 structure
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Common Name | UNC10201652 | ||
|---|---|---|---|---|
| CAS Number | 372495-52-8 | Molecular Weight | 411.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H25N7OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UNC10201652UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes[1][2]. |
| Name | UNC10201652 |
|---|
| Description | UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes[1][2]. |
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| Related Catalog | |
| Target |
IC50: 0.117 μM (E. coli GUS)[1] EC50: 74±7 nM (E. coli)[1] |
| In Vitro | UNC10201652 exhibits potently inhibitory activity against wild type E. coli with an EC50 of 74±7 nM[2]. |
| References |
| Molecular Formula | C20H25N7OS |
|---|---|
| Molecular Weight | 411.52 |