onjisaponin B structure
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Common Name | onjisaponin B | ||
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| CAS Number | 35906-36-6 | Molecular Weight | 1573.671 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C75H112O35 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of onjisaponin BOnjisaponin B is a natural product derived from Radix Polygalae. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells, and exbibits potential therapeutic effects on Parkinson disease and Huntington disease[1]. |
| Name | Senegin III |
|---|---|
| Synonym | More Synonyms |
| Description | Onjisaponin B is a natural product derived from Radix Polygalae. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells, and exbibits potential therapeutic effects on Parkinson disease and Huntington disease[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C75H112O35 |
| Molecular Weight | 1573.671 |
| Exact Mass | 1572.698364 |
| PSA | 544.57000 |
| LogP | 1.78 |
| Index of Refraction | 1.656 |
| InChIKey | QSTBHNPMHXYCII-KJCIHCEPSA-N |
| SMILES | COc1ccc(C=CC(=O)OC2C(C)OC(OC(=O)C34CCC(C)(C)CC3C3=CCC5C6(C)CC(O)C(OC7OC(CO)C(O)C(O)C7O)C(C)(C(=O)O)C6CCC5(C)C3(CO)CC4)C(OC3OC(C)C(OC4OCC(OC5OC(CO)C(O)C(O)C5O)C(O)C4O)C(O)C3O)C2OC2OC(C)C(O)C(O)C2O)cc1 |
| 6-Deoxy-α-L-mannopyranosyl-(1->3)-[β-D-galactopyranosyl-(1->4)-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)]-6-deoxy-1-O-[(2β,3β)-3-(β-D-glucopyranosyloxy)-2,23,27
 -trihydroxy-23,28-dioxoolean-12-en-28-yl]-4-O-[(2E)-3-(4-methoxyphenyl)-2-propenoyl]-β-D-galactopyranose |
| onjisaponin B |
| Onjisaponin-B |
| β-D-Galactopyranose, O-6-deoxy-α-L-mannopyranosyl-(1->3)-O-[O-β-D-galactopyranosyl-(1->4)-O-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)]-6-deoxy-1-O-[(2β,3β)-3-(b
 η-D-glucopyranosyloxy)-2,23,27-trihydroxy-23,28-dioxoolean-12-en-28-yl]-4-O-[(2E)-3-(4-methoxyphenyl)-1-oxo-2-propen-1-yl]- |