ligstroside
Modify Date: 2024-01-04 13:38:30
ligstroside structure
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Common Name | ligstroside | ||
|---|---|---|---|---|
| CAS Number | 35897-92-8 | Molecular Weight | 524.514 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 736.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C25H32O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 245.1±26.4 °C | |
Use of ligstrosideLigustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages[1][2]. |
| Name | Ligustroside |
|---|---|
| Synonym | More Synonyms |
| Description | Ligustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages[1][2]. |
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| Related Catalog | |
| In Vitro | Ligstroside increases mRNA expression of SIRT1, CREB1, complex I, and GPx1 in SH-SY5Y-APP695 cells[1]. |
| In Vivo | Ligstroside (50 mg/kg; a supplemented diet for 6 months) protects against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing[1]. Animal Model: Female NMRI mice, aged 12 months[1] Dosage: 50 mg/kg Administration: Received a supplemented diet for 6 months (equivalent to 6.25 mg/kg b.w.) Result: Showed improved spatial working memory; Restored brain ATP levels in aged mice and led to a significant life extension compared to aged control animals. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 736.9±60.0 °C at 760 mmHg |
| Molecular Formula | C25H32O12 |
| Molecular Weight | 524.514 |
| Flash Point | 245.1±26.4 °C |
| Exact Mass | 524.189392 |
| PSA | 181.44000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Hazard Codes | Xi |
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| Precursor 0 | |
|---|---|
| DownStream 2 | |
CAS#:2280-44-6
CAS#:501-94-0| 2H-Pyran-4-acetic acid, 3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(4-hydroxyphenyl)ethyl ester, (2S,3E,4S)- |
| Methyl (2S,3E,4S)-3-ethylidene-2-(β-D-glucopyranosyloxy)-4-{2-[2-(4-hydroxyphenyl)ethoxy]-2-oxoethyl}-3,4-dihydro-2H-pyran-5-carboxylate |
| 2H-Pyran-4-acetic acid, 3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-, 2-(4-hydroxyphenyl)ethyl ester, (2R,3E,4S)- |
| Methyl (2R,3E,4S)-3-ethylidene-2-(β-D-glucopyranosyloxy)-4-{2-[2-(4-hydroxyphenyl)ethoxy]-2-oxoethyl}-3,4-dihydro-2H-pyran-5-carboxylate |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: ligstroside
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Ligustroside
- Price: ￥3750.0/5mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: ligstroside
- Price: ￥4000.0/5mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Ligustroside
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: LIGUSTROSIDE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥2500/1 mg
Reference only. check more ligstroside price