5-methoxyuridine

Modify Date: 2025-08-25 09:28:14

5-methoxyuridine Structure
5-methoxyuridine structure
Common Name 5-methoxyuridine
CAS Number 35542-01-9 Molecular Weight 274.23
Density 1.65±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C10H14N2O7 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of 5-methoxyuridine


5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-methoxyuridine
Synonym More Synonyms

 5-methoxyuridine Biological Activity

Description 5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.65±0.1 g/cm3(Predicted)
Molecular Formula C10H14N2O7
Molecular Weight 274.23
Exact Mass 274.08000
PSA 134.01000
Storage condition 2-8°C

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles7

More Articles
Codon recognition by tRNA molecules with a modified or unmodified uridine at the first position of the anticodon.

Nucleic Acids Symp. Ser. 34 , 203-204, (1995)

Effects of a single nucleoside modification at the first position of the anticodon of a transfer RNA molecule on its codon reading properties were investigated by use of a cell-free protein synthesis....

5-methoxyuridine: a new minor constituent located in the first position of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis.

Nucleic Acids Res. 3 , 2851-2860, (1976)

The sequences of the anticodon of tRNAAla, tRNAThr, and tRNAVal from Bacillus subtilis W 168 were N-G-C, N-G-U, and N-A-C, respectively. A new minor constituent, N, occupied the first position of the ...

Bacillus subtilis tRNA(Pro) with the anticodon mo5UGG can recognize the codon CCC.

Biochim. Biophys. Acta 1728 , 143-149, (2005)

In Bacillus subtilis, four codons, CCU, CCC, CCA, and CCG, are used for proline. There exists, however, only one proline-specific tRNA having the anticodon mo(5)UGG. Here, we found that this tRNA(Pro)...

 Synonyms

5-OMe-uridine
5-METHOXYURIDINE
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