(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE

Modify Date: 2025-08-25 18:15:08

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Structure
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE structure
 Common Name (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE
CAS Number 354811-10-2 Molecular Weight 261.30
Density N/A Boiling Point N/A
Molecular Formula C12H11N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE


IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs[1].

 Names

Name 2-(carbamoylamino)-5-phenylthiophene-3-carboxamide
Synonym More Synonyms

  Biological Activity

Description IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs[1].
Related Catalog
Target

IKK-2:25 nM (IC50)

References

[1]. Baxter A, et, al. Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2817-22.  

 Chemical & Physical Properties

Molecular Formula C12H11N3O2S
Molecular Weight 261.30
Exact Mass 261.05700
PSA 128.43000
LogP 3.47560

 Synonyms

IN1462
HMS3229F13
HMS2043P17
IKK-2 Inhibitor VI
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Chemsrc provides CAS#:354811-10-2 MSDS, density, melting point, boiling point, structure, etc. Its name is (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE>> amp version: (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE

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