(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE

Names

[ Name ]:
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE

[Synonym ]:
IN1462
HMS3229F13
HMS2043P17
IKK-2 Inhibitor VI

[Description]:

IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> IKK

Research Areas >> Inflammation/Immunology

[Target]

IKK-2:25 nM (IC50)

[References]

[ Molecular Formula ]:
C₁₂H₁₁N₃O₂S

[ Molecular Weight ]:
261.30

[ Exact Mass ]:
261.05700

[ PSA ]:
128.43000

[ LogP ]:
3.47560