CBA
Modify Date: 2025-12-01 21:21:05
CBA structure
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Common Name | CBA | ||
|---|---|---|---|---|
| CAS Number | 351424-20-9 | Molecular Weight | 340.158 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 576.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C15H11Cl2NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 302.4±30.1 °C | |
Use of CBATRPM4 inhibitor 5 is a potent and selective inhibitor of TRPM4 with IC50 of 1.5 uM (Na+ influx); selectively inhibits TRPM4 overexpressed in HEK293 cells (IC50=1.8 uM) using classical patch-clamp electrophysiology recordings, shows no significant effect on the TRPM5 current, as well as other TRP family members including TRPM7, TRPM8, TRPV1 and TRPV6. |
| Name | 4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | TRPM4 inhibitor 5 is a potent and selective inhibitor of TRPM4 with IC50 of 1.5 uM (Na+ influx); selectively inhibits TRPM4 overexpressed in HEK293 cells (IC50=1.8 uM) using classical patch-clamp electrophysiology recordings, shows no significant effect on the TRPM5 current, as well as other TRP family members including TRPM7, TRPM8, TRPV1 and TRPV6. |
|---|---|
| References | References 1. Ozhathil LC, et al. Br J Pharmacol. 2018 Jun;175(12):2504-2519. View Related Products by Target TRP Channel |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 576.4±50.0 °C at 760 mmHg |
| Molecular Formula | C15H11Cl2NO4 |
| Molecular Weight | 340.158 |
| Flash Point | 302.4±30.1 °C |
| Exact Mass | 339.006500 |
| LogP | 4.95 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.656 |
| Benzoic acid, 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]- |
| 4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid |