cp028

Modify Date: 2025-08-27 11:14:29

Use of cp028

cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 µM[1].

Name	cp028

Description	cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 µM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
References	[1]. Sidarovich A, et al. Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. Elife. 2017 Mar 16;6:e23533.

Molecular Formula	C₂₃H₁₇FN₂O₄
Molecular Weight	404.39
InChIKey	KKBJKSJVJPXCRA-QGOAFFKASA-N
SMILES	CCc1ccccc1N1C(=O)NC(=O)C(=Cc2ccc(-c3ccc(F)cc3)o2)C1=O