cp028

Names

[ CAS No. ]:
347397-83-5

[ Name ]:
cp028

Biological Activity

[Description]:

cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 µM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Sidarovich A, et al. Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. Elife. 2017 Mar 16;6:e23533.  

Chemical & Physical Properties

[ Molecular Formula ]:
C23H17FN2O4

[ Molecular Weight ]:
404.39


Related Compounds

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