Isoproturon

Modify Date: 2024-01-02 19:09:22

Isoproturon structure	Common Name	Isoproturon
	CAS Number	34123-59-6	Molecular Weight	206.284
	Density	1.1±0.1 g/cm3	Boiling Point	353.2±25.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₁₈N₂O	Melting Point	155-156ºC
	MSDS	Chinese USA	Flash Point	167.4±23.2 °C
	Symbol	GHS07, GHS08, GHS09	Signal Word	Warning

Use of Isoproturon

Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[1][2].

Name	isoproturon
Synonym	More Synonyms

Description	Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Feng Fan Lu, et al. Isoproturon-Induced Salicylic Acid Confers Arabidopsis Resistance to Isoproturon Phytotoxicity and Degradation in Plants. J Agric Food Chem. 2018 Dec 19;66(50):13073-13083. [2]. Mian Muhammad, et al. Determination of Isoproturon in Environmental Samples Using the QuEChERS Extraction-Spectrofluorimetric Method. Environ Toxicol Chem. 2019 Dec;38(12):2614-2620.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Feng Fan Lu, et al. Isoproturon-Induced Salicylic Acid Confers Arabidopsis Resistance to Isoproturon Phytotoxicity and Degradation in Plants. J Agric Food Chem. 2018 Dec 19;66(50):13073-13083.

[2]. Mian Muhammad, et al. Determination of Isoproturon in Environmental Samples Using the QuEChERS Extraction-Spectrofluorimetric Method. Environ Toxicol Chem. 2019 Dec;38(12):2614-2620.

Density	1.1±0.1 g/cm3
Boiling Point	353.2±25.0 °C at 760 mmHg
Melting Point	155-156ºC
Molecular Formula	C₁₂H₁₈N₂O
Molecular Weight	206.284
Flash Point	167.4±23.2 °C
Exact Mass	206.141907
PSA	32.34000
LogP	2.32
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.555
Storage condition	APPROX 4°C

Isoproturon MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YT0170000

CHEMICAL NAME :: Urea, 1,1-dimethyl-3-(p-isopropylphenyl)-

CAS REGISTRY NUMBER :: 34123-59-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C12-H18-N2-O

MOLECULAR WEIGHT :: 206.32

WISWESSER LINE NOTATION :: 1Y1&R DMVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1826 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >670 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1043 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: >9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - pigeon

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 3042 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 48 gm/kg/10W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in spleen

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 21 gm/kg/3W-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg/5D (Intermittent)

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 28,862,1990

Symbol	GHS07, GHS08, GHS09
Signal Word	Warning
Hazard Statements	H332-H351-H410
Precautionary Statements	P273-P281-P501
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R40;R50/53
Safety Phrases	S36/37-S60-S61-S26
RIDADR	UN 3077
RTECS	YT0170000
Packaging Group	III
HS Code	2924299039

4-Isopropylaniline

CAS#:99-88-7

dmcl

CAS#:79-44-7

~10%

Isoproturon

CAS#:34123-59-6

Literature: Degani, Iacopo; Fochi, Rita; Magistris, Claudio; Migliaccio, Mara Synthesis, 2009 , # 5 p. 801 - 808

4-Isopropylphen...

CAS#:31027-31-3

Dimethylamine

CAS#:124-40-3

Isoproturon

CAS#:34123-59-6

Literature: Journal of the Chemical Society, Perkin Transactions 2, , # 11 p. 2226 - 2229

Precursor 4
CAS#:99-88-7 4-Isopropylaniline CAS#:79-44-7 dmcl CAS#:31027-31-3 4-Isopropylphen... CAS#:124-40-3 Dimethylamine
DownStream 6
CAS#:74-89-5 methylamine CAS#:598-94-7 1,1-DIMETHYLUREA CAS#:99-88-7 4-Isopropylaniline CAS#:31027-31-3 4-Isopropylphen...
CAS#:124-40-3 Dimethylamine CAS#:7260-94-8 dimethylcarbami...

HS Code	2924299039
Summary	2924299039. VAT:17.0%. Tax rebate rate:9.0%. Supervision conditions:S(import or export registration certificate for pesticides). MFN tariff:6.5%. General tariff:30.0%

Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.

J. Chromatogr. A. 1418 , 140-9, (2015)

The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of...

Simultaneous extraction and determination of various pesticides in environmental waters.

J. Sep. Sci. 37(24) , 3699-705, (2014)

A simple and rapid method was developed for the simultaneous analysis of nine different pesticides in water samples by gas chromatography with mass spectrometry. A number of parameters that may affect...

Multiresidue method for the determination of 13 pesticides in three environmental matrices: water, sediments and fish muscle.

Talanta 85(3) , 1500-7, (2011)

Pesticides residues in aquatic ecosystems are an environmental concern which requires efficient analytical methods. In this study, we proposed a generic method for the quantification of 13 pesticides ...

N,N-Dimethyl-N'-(4-(1-methylethyl)phenyl)urea

N,N-Dimethyl-N'-[4-(1-methylethyl)phenyl]urea

Protugan

N,N-dimethyl-N’-[4-(1-methylethyl)phenyl]urea

Tolkan

1,1-dimethyl-3-[4-(propan-2-yl)phenyl]urea

I.P.U.

Isoproturon

Graminon

Urea, N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]-

Nocilon

EINECS 251-835-4

MFCD00078684

3-(4-Isopropylphenyl)-1,1-dimethylurea

3-p-Cumenyl-1,1-dimethylurea

Alon

Arelon

Belgran

1,1-dimethyl-3-(4-propan-2-ylphenyl)urea

Zodiac TX

N-(4-Isopropylphenyl)-N',N'-dimethylurea

Arelon R

N,N-dimethyl-N’-[4-(propan-2-yl)phenyl]urea

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Isoproturon
Price: ￥218.0/1ml
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Isoproturon
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Isoproturon
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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