1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
Modify Date: 2024-01-04 21:09:28
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one structure
|
Common Name | 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one | ||
|---|---|---|---|---|
| CAS Number | 332371-82-1 | Molecular Weight | 294.34 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 542.0±45.0 °C at 760 mmHg | |
| Molecular Formula | C19H18O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 295.7±25.2 °C | |
Use of 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2]. |
| Name | 1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one |
|---|---|
| Synonym | More Synonyms |
| Description | 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 2) (1-10 µM) inhibits melanogenesis in B16 melanoma 4A5 cells with an IC50 of 1.99 µM[2]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 542.0±45.0 °C at 760 mmHg |
| Molecular Formula | C19H18O3 |
| Molecular Weight | 294.34 |
| Flash Point | 295.7±25.2 °C |
| Exact Mass | 294.125580 |
| PSA | 57.53000 |
| LogP | 2.89 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.648 |
| Hazard Codes | Xi |
|---|
| 4,6-Heptadien-3-one, 1,7-bis(4-hydroxyphenyl)-, (4E,6E)- |
| (4E,6E)-1,7-Bis(4-hydroxyphenyl)-4,6-heptadien-3-one |