1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one

Modify Date: 2025-08-25 19:45:57

1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one structure	Common Name	1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
	CAS Number	332371-82-1	Molecular Weight	294.34
	Density	1.2±0.1 g/cm3	Boiling Point	542.0±45.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₁₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	295.7±25.2 °C

Use of 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2].

Name	1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
Synonym	More Synonyms

Description	1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 µM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 2) (1-10 µM) inhibits melanogenesis in B16 melanoma 4A5 cells with an IC50 of 1.99 µM[2].
References	[1]. Ali MS, et al. Six new diarylheptanoids from the seeds of Alpinia blepharocalyx. J Nat Prod. 2001 Mar;64(3):289-93. [2]. Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81.

Density	1.2±0.1 g/cm3
Boiling Point	542.0±45.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₈O₃
Molecular Weight	294.34
Flash Point	295.7±25.2 °C
Exact Mass	294.125580
PSA	57.53000
LogP	2.89
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.648

Hazard Codes	Xi

4,6-Heptadien-3-one, 1,7-bis(4-hydroxyphenyl)-, (4E,6E)-

(4E,6E)-1,7-Bis(4-hydroxyphenyl)-4,6-heptadien-3-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1,7-Bis(4-hydroxyphenyl)hepta-4,
Price: Check
Purity: 98.0%
Delivery: 10 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.