CFM-4
Modify Date: 2025-09-21 12:27:23
CFM-4 structure
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Common Name | CFM-4 | ||
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| CAS Number | 331458-02-7 | Molecular Weight | 405.90 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H16ClN3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CFM-4CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells[1]. |
| Name | 1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro[indoline-3,2'-[1.3.4]thiadiazol]-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | CFM-4 is a potent small molecular antagonist of CARP-1/APC-2 binding. CFM-4 prevents CARP-1 binding with APC-2, causes G2M cell cycle arrest, and induces apoptosis with an IC50 range of 10-15 μM. CFM-4 also suppresses growth of drug-resistant human breast cancer cells[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C22H16ClN3OS |
|---|---|
| Molecular Weight | 405.90 |
| Exact Mass | 405.07000 |
| PSA | 70.00000 |
| LogP | 4.56720 |
| CFM-4 |
| L-703,664 succinate |